Prentice Hall

Engineering

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Bioengineering Fundamentals
Ann Saterbak, Rice University
Ka-Yiu San, Rice University
Larry V McIntire, Georgia Tech University

ISBN-10: 0130938386
ISBN-13: 9780130938381

Publisher: Prentice Hall
Copyright: 2007
Format: Cloth; 552 pp
Published: 01/05/2007

Suggested retail price: $154.00
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For sophomore-level courses in bioengineering, biomedical engineering, and related fields.

 

Combining engineering principles with technical rigor and a problem-solving focus, this textbook takes a unifying, interdisciplinary approach to the conservation laws that form the foundation of bioengineering: mass, energy, charge, and momentum.

• Solutions Manual - available upon request.  Please contact Jenn Lonschein (Jennifer.Lonschein@pearson.com) or Mack Patterson (Mack.Patterson@pearson.com)  

• Fundamental concepts and equations that unify all engineering curricula — Demonstrates how conservation laws (including conservation of mass and energy, momentum, and charge) apply to biological and medical systems to lay a foundation for beginning bioengineers.

• Focus on practical skill development — Designed to assist students in acquiring skills useful in the field, such as: problem formulation and solving; understanding of mass, momentum, charge, and energy conservation equations; the application of conservation equations to problems in the biological and medical sciences, and an appreciation for the field’s technical challenges and opportunities.

• Mastery of conservation principles — Delivers essential knowledge as students transition from general science and math courses to upper-level bioengineering courses, such as biomaterials and bioinstrumentation.

• Framework of accounting and conservation principles (Ch. 2) — Allows students to build a mental model of how key concepts in engineering, chemistry, and physics are interrelated. Emphasizes how accounting and conservation equations are used to derive familiar laws, such as Kirchhoff’s current and voltage laws, Newton’s laws of motions, Bernoulli’s equation, and others.

• Emphasis on problem-solving strategies — Usesextensive example problems that are worked out in detail to demonstrate the translation of written problem statements into a diagram.

• Wide array of examples using actual numerical parameters — Topics span the breadth of modern bioengineering, including physiology, biochemistry, tissue engineering, biotechnology, and instrumentation, giving students exposure to current bioengineering technology and research.

• Quantitative engineering approach and exposure to bioengineering technologies and research topics (Ch. 1) — Introduces physical variables in the context of bioengineering, and the methodology for solving engineering problems that is used throughout the text.

• Conservation of mass, energy, charge, and momentum (Chs. 3-6) — Opens each chapter with a timely bioengineering research or design challenge to expose students to the realities of the field.

• Detailed biomedical applications (Ch. 7) — Features three case studies on heart and blood circulation, lungs and a heart-lung bypass machine, and kidneys and dialysis, that are designed to bridge the applications of the mass, energy, charge, and momentum accounting and conservation equations in biomedical systems. Appropriate for use as either core or supplementary material, or as the basis for large-scale problem-based projects.

• Self-contained chapters and flexible organization — Simplifies the process of customizing material to fit unique class demands.  Instructors can choose to emphasize one or more extensive properties, or to teach from an entirely problem-based learning framework.

     1.   Introduction to Engineering Calculation

          1.1  Instructional Objectives

          1.2  Physical Variables, Units, and Dimensions

          1.3  Unit Conversion

          1.4  Dimensional Analysis

          1.5  Specific Physical Variables

              1.5.1 Extensive and Intensive Properties 

              1.5.2 Scalar and Vector Quantities

              1.5.3 Applications

                   1.5.3.1 Parkinson’s Disease

                   1.5.3.2 Mars Surface Conditions

                   1.5.3.3 Getting to Mars

                   1.5.3.4 Gene Transfer Technology

                   1.5.3.5 Microsurgical Assistant

                   1.5.3.6 Victoria Falls

          1.5  Quantization and Data Presentation

          1.6  Solving Systems of Linear Equations in MATLAB

          1.7  Methodology for Solving Engineering Problems

              References

              Problems

     2.   Foundations of Conservation Principles

          2.1  Instructional Objectives

          2.2  Introduction to the Conservation Laws

          2.3  Counting Extensive Properties in a System

          2.4  Accounting and Conservation Equations

               2.4.1 Algebraic Accounting Statements

              2.4.2 Differential Accounting Statements

              2.4.3 Integral Accounting Statements

              2.4.4 Algebraic Conservation Equation

              2.4.5 Differential Conservation Equation

              2.4.6 Integral Conservation Equation

          2.5  System Descriptions

              2.5.1 Describing the Input and Output Terms

2.5.2 Describing the Generation and Consumption
      Terms

              2.5.3 Describing the Accumulation Term

              2.5.4 Changing Your Assumptions Changes how a
                     System is Described

2.6  Summary of use of Accounting and Conservation Equations

              Problems

     3.   Conservation of Mass

          3.1  Instructional Objectives and Motivation

              3.1.1 Tissue Engineering

          3.2  Basic Mass Concepts

3.3  Review of Mass Accounting and Conservation Statements

          3.4  Open, Non-Reacting, Steady-State Systems

3.5  Steady-State Systems with Multiple Inlets and Outlets

          3.6  Systems with Multicomponent Mixtures

          3.7  Systems with Multiple Units

          3.8  Systems with Chemical and Biochemical Reactions

          3.9  Dynamic systems

              References

              Problems

     4.   Conservation of Energy

          4.1  Instructional Objectives and Motivation

              4.1.1 Bioenergy

          4.2  Basic Energy Concepts

              4.2.1 Energy Possessed by Mass

              4.2.2 Energy in Transition

              4.2.3 Enthalpy

          4.3  Review of Energy Conservation Statements

          4.4  Closed and Isolated Systems

          4.5  Calculation of Enthalpy in Non-Reactive Processes

              4.5.1 Enthalpy as a State Function

              4.5.2 Change in Temperature

              4.5.3 Change in Pressure

              4.5.4 Changes in Phase

              4.5.5 Mixing Effects

4.6  Open, Steady-State Systems-No Potential or Kinetic Energy Changes

4.7  Open, Steady-State Systems with Potential or Kinetic Energy Changes

          4.8  Calculation of Enthalpy in Reactive Processes

              4.8.1 Heat of Reaction

              4.8.2 Heat of Formation and Heat of Combustion

4.8.3 Heat of Reaction Calculations
      at Non-Standard Conditions

          4.9  Open Systems with Reactions

          4.10 Dynamic Systems

              References

              Problems

     5.   Conservation of Charge

          5.1  Instructional Objectives and Motivation

              5.1.1 Neurosensors

          5.2  Basic Charge Concepts

              5.2.1 Charge

              5.2.2 Current

              5.2.3 Coulomb’s Law and Electric Fields

              5.2.4 Electrical Energy

5.3  Review of Charge Accounting and Conservation Statements

5.3.1 Accounting Equations for Positive
      and Negative Charge

              5.3.2 Conservation Equation for Net Charge

          5.4  Review of Electrical Energy Accounting Statement

          5.5  Kirchhoff’s Current Law (KCL)

          5.6  Kirchhoff’s Voltage Law (KVL)

              5.6.1 Elements that Generate Electrical Energy

              5.6.2 Elements that Consume Electrical Energy

              5.6.3 Discussion and Derivation of KVL

              5.6.4 Einthoven’s Law

          5.7  Dynamic Systems

          5.8  Dynamic Systems and Electrical Energy

          5.9  Reacting Systems-Focus on Charge

              5.9.1 Radioactive Decay

              5.9.2 Acids and Bases

              5.9.3 Electrochemical Reactions

          5.10 Reacting Systems-Focus on Electrical Energy

              References

              Problems

     6.   Conservation of Momentum

          6.1  Instructional Objectives and Motivation

              6.1.1 Bicycle Kinematics

          6.2  Basic Momentum Concepts

6.2.1 Transfer of Linear Momentum Possessed
      by Mass

6.2.2 Transfer of Linear Momentum Contributed
      by Forces

6.2.3 Transfer of Angular Momentum Possessed
           by Mass

6.2.4 Transfer of Angular Momentum Contributed
      by Forces

6.2.5 Definition of Particles, Rigid Bodies,
      and Fluids

          6.3  Review of Linear Momentum Conservation Statements

6.4  Review of Angular Momentum Conservation Statements

          6.5  Rigid-Body Statics

          6.6  Fluid Statics

          6.7  Isolated, Steady-State Systems

6.8  Steady-State Systems with Movement
of Mass Across System Boundaries

          6.9  Unsteady-State Systems

          6.10 Reynolds Number

          6.11 Mechanical Energy and Bernoulli Equations

              6.11.1 Mechanical Energy Accounting Equation

              6.11.2 Bernoulli Equation

6.11.3 Additional Applications Using the
            Mechanical Energy and Bernoulli Equations

              References

              Problems

     7.   Case Studies

          7.A  Breathe Easy: The Human Lungs

          Background Information

          References

          Problems Focusing on the Human Lungs

     7.B  Keeping the Beat: The Human Heart

          Background Information

          References

          Problems Focusing on the Human Heart

     7.C  On Your Way Out: The Human Kidneys

          Background Information

          References

          Problems Focusing on the Human Kidneys

          Appendices

          Appendix A: List of Symbols

          Appendix B: Factors for Unit Conversion

          Appendix C: Periodic Table of Elements

          Appendix D: Tables of Biological Data

          Appendix E: Thermodynamic Data

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